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Fine-tuning neural circuits to heal the brain – Segerfalk lecturer Andres Lozano on next-gen neurosurgery

LONGREAD. He treats tremor with sound waves, is preparing to help paralyzed patients control a cursor with their thoughts and envisions a future where brain and machines talk to each other in both directions. Neurosurgeon and researcher Andres Lozano is pushing the boundaries of what is possible in the human brain – and doing it with both precision and imagination. “We are trying to discover the b

https://www.medicine.lu.se/article/fine-tuning-neural-circuits-heal-brain-segerfalk-lecturer-andres-lozano-next-gen-neurosurgery - 2025-11-03

More opportunities to test for Alzheimer’s using new analytical method

A simpler method of analysing blood samples for Alzheimer’s disease has been tested in a large multicentre study, led by Lund University in Sweden. “This is a major step in bringing simple blood tests for Alzheimer’s disease into the healthcare system globally,” say the researchers behind the study. In brief:The blood-based marker (P-tau217) may start to change several years before the onset of Al

https://www.medicine.lu.se/article/more-opportunities-test-alzheimers-using-new-analytical-method - 2025-11-03

From molecule to patient – Six promising projects to advance Parkinson's research

What role does an inflammatory protein have in disease development? Which neuronal circuits cause different symptoms? How may diabetes affect Parkinson’s disease? Can motor signs be identifies early in individuals at risk for the disease? And how should patients in very advanced disease stages be treated to maintain their quality of life? These questions may soon have answers thanks to several ong

https://www.medicine.lu.se/article/molecule-patient-six-promising-projects-advance-parkinsons-research - 2025-11-03

Simple medication can save the lives of cardiac patients

Patients suffering from myocardial infarction who receive early add-on lipid-lowering medication have a significantly better prognosis than those who receive add-on treatment late, or not all. Based on the results of a study from Lund University in Sweden, many new heart attacks, strokes and deaths could be prevented. Cardiovascular disease is by far the most common cause of death worldwide, and m

https://www.medicine.lu.se/article/simple-medication-can-save-lives-cardiac-patients - 2025-11-03

Lund Stem Cell Center welcomes a new leadership team

The Lund Stem Cell Center at Lund University welcomes the beginning of a new chapter with the appointment of its new leadership team. As of January 1, 2025, Professor Malin Parmar has assumed the role of Director, with Associate Professor Göran Karlsson stepping in as Deputy Director. Together, they bring decades of expertise, deep connections to the Lund research community, and a shared vision fo

https://www.medicine.lu.se/article/lund-stem-cell-center-welcomes-new-leadership-team - 2025-11-03

Protein changes reveal diseases

Researchers at Lund University have developed a new method to determine how the composition of proteins in blood changes in response to disease or organ damage. This could provide a deeper understanding of how diseases affect the body and be used to discover new biomarkers in the blood to aid in diagnosing complex medical conditions. Our organs consist of a variety of specific proteins that are vi

https://www.medicine.lu.se/article/protein-changes-reveal-diseases - 2025-11-03

Higher success rate using a simple oral swab test before IVF

Researchers at Lund University in Sweden have conducted a clinical study to show how a woman’s genetic profile provides information on which hormone treatment is most effective for in vitro fertilisation (IVF). The researchers have now developed a simple oral swab test that shows which hormone therapy is the best option for IVF treatment About 15 per cent of all couples of reproductive age are inv

https://www.medicine.lu.se/article/higher-success-rate-using-simple-oral-swab-test-ivf - 2025-11-03

8.3 million euros for doctoral programme in regenerative medicine and ATMP

Lund University in Sweden has been awarded an EU grant of 8.3 million euros for a new international doctoral programme in regenerative medicine and advanced therapy medicinal products. The aim is to improve the environment for regenerative medicine and ATMPs in Europe and facilitate cooperation between research and clinical application. It started as an idea at the Lund Stem Cell Center to train a

https://www.medicine.lu.se/article/83-million-euros-doctoral-programme-regenerative-medicine-and-atmp - 2025-11-03

Lund University's virus centre inaugurated with symbolic demolition of giant virus

Lund University Virus Centre (LUVC) holds festive inauguration (May 27). There was no ribbon-cutting ceremony, but instead a symbolic demolition of a 3D-printed giant virus marked the official opening of the virus centre.Three deans—current and former—as well as professors who have succeeded one another at the Faculty of Medicine and played key roles in bringing LUVC to life, attended the ceremony

https://www.medicine.lu.se/article/lund-universitys-virus-centre-inaugurated-symbolic-demolition-giant-virus - 2025-11-03

New gene variants significantly increase the risk of blood clots

Blood clots can form in both arteries and veins. However, the reasons behind them differ, as do the consequences and the chances of preventing blood clots. In Sweden, almost half of all cases of venous thrombosis have a genetic explanation. A team of researchers from Lund University in Sweden has now discovered three gene variants that increase the risk of blood clots in the leg by up to 180 perce

https://www.medicine.lu.se/article/new-gene-variants-significantly-increase-risk-blood-clots - 2025-11-03

Link identified between low-fibre diet and the more dangerous type of atherosclerotic plaque in the coronary arteries

A Swedish multi-centre study led by researchers at Lund University shows a link between low fibre consumption and the presence of unstable or high-risk plaque in coronary arteries – the type of plaque that can trigger blood clots and cause heart attacks. The study also links dietary pattern to the composition of the plaques, i.e. how potentially dangerous they are. Using advanced cardiac imaging,

https://www.medicine.lu.se/article/link-identified-between-low-fibre-diet-and-more-dangerous-type-atherosclerotic-plaque-coronary2 - 2025-11-03

How to turn research ideas into a real-world impact

Professors Carl Borrebaeck, Thoas Fioretos, Lao Saal and Åke Borg share their experiences in transforming groundbreaking research into diagnostic tools, treatments, and biotech companies. From navigating commercialization strategies and securing long-term funding to building strong teams and mentoring future innovators, they reflect on what it truly takes to make science matter—outside the lab. Th

https://www.medicine.lu.se/article/how-turn-research-ideas-real-world-impact - 2025-11-03

Charlotte Ling receives major grant for clinical diabetes research

Congratulations to Charlotte Ling who, together with Katarina Fagher and Alice Maguolo, has been awarded a grant of five million Danish kroner by the Novo Nordisk Foundation. The funding will support clinical research in precision medicine, focusing on epigenetic analysis of blood samples from 13,000 individuals. Epigenetic research paves the way for tailored type 2 diabetes treatmentCharlotte Lin

https://www.medicine.lu.se/article/charlotte-ling-receives-major-grant-clinical-diabetes-research - 2025-11-03

Brain activation pattern behind impulsivity in Parkinson’s treatment discovered

An experimental study from Lund University reveals for the first time that different Parkinson’s medications affect brain activity in distinct ways. This could explain why some patients develop impulsive and compulsive behaviors as a result of their treatment. The findings have been published in NPJ Parkinson’s Disease. Upon receiving treatment for their motor symptoms, many patients with Parkinso

https://www.medicine.lu.se/article/brain-activation-pattern-behind-impulsivity-parkinsons-treatment-discovered - 2025-11-03

Brussels meeting: Advancing personalised treatment for childhood AML across Europe

In June, pediatric cancer experts from 16 countries gathered in Brussels for the annual meeting of the NOPHO-DB-SHIP consortium—an EU-wide collaboration working to improve outcomes for children with Acute Myeloid Leukemia (AML). In Sweden, the trial is coordinated by Lund University and Skåne University Hospital. At the center of this collaboration is the CHIP-AML22 trial—an international phase II

https://www.medicine.lu.se/article/brussels-meeting-advancing-personalised-treatment-childhood-aml-across-europe - 2025-11-03

Aggressive skin cancer driven by mitochondrial processes –existing drugs offer promising treatment path

A new study led by researchers at Lund University in Sweden, reveals that melanoma, the deadliest form of skin cancer, can in some cases be driven by mitochondrial processes, which can be effectively targeted using existing drugs. In preclinical laboratory experiments with melanoma cell cultures, researchers successfully eliminated cancer cells by using antibiotics and inhibitors of mitochondrial

https://www.medicine.lu.se/article/aggressive-skin-cancer-driven-mitochondrial-processes-existing-drugs-offer-promising-treatment-path - 2025-11-03

Biomarkers reveal risk of cardiovascular disease in type 2 diabetes

An international research team led from Lund University, has identified epigenetic biomarkers that can predict which people with type 2 diabetes are at risk of cardiovascular disease. The study is now published in Cell Reports Medicine. People with type 2 diabetes are up to four times more likely to have heart attacks, strokes, anginas and other coronary heart diseases than healthy people. Therefo

https://www.medicine.lu.se/article/biomarkers-reveal-risk-cardiovascular-disease-type-2-diabetes - 2025-11-03

Children waiting for a new heart –study shows marked improvement in survival rates and the importance of Nordic cooperation

In a new observational study, researchers at Lund University in Sweden looked at all children listed for heart transplants in the Nordic countries between 1986 and 2023. A total of 597 children were included in the study, 461 of whom received a transplant. The results show that survival rates have increased significantly over time despite the modest volumes in the region – a development that the r

https://www.medicine.lu.se/article/children-waiting-new-heart-study-shows-marked-improvement-survival-rates-and-importance-nordic - 2025-11-03

Hjelt Diabetes Foundation supports research that can pave the way for new cell therapies

Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. The Bo and Kerstin Hjelt Diabetes Foundation provides support to two diabetes researchers at Lund University Diabetes Centre who contribute with new knowledge to this research field. Type 1 diabetes is a condition wh

https://www.medicine.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-11-03

Why repetitive DNA matters for human brain evolution and disease

For decades, large stretches of human DNA were dismissed as ‘junk’ and considered to serve no real purpose. In a new study in Cell Genomics, researchers at Lund University in Sweden show that the repetitive part of the human genome plays an active role during early brain development and may also be relevant for understanding brain diseases. DNA carries the complete set of instructions an organism

https://www.medicine.lu.se/article/why-repetitive-dna-matters-human-brain-evolution-and-disease-0 - 2025-11-03