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Biomarkers reveal risk of cardiovascular disease in type 2 diabetes

An international research team led from Lund University, has identified epigenetic biomarkers that can predict which people with type 2 diabetes are at risk of cardiovascular disease. The study is now published in Cell Reports Medicine. People with type 2 diabetes are up to four times more likely to have heart attacks, strokes, anginas and other coronary heart diseases than healthy people. Therefo

https://www.medicine.lu.se/article/biomarkers-reveal-risk-cardiovascular-disease-type-2-diabetes - 2025-10-29

Children waiting for a new heart –study shows marked improvement in survival rates and the importance of Nordic cooperation

In a new observational study, researchers at Lund University in Sweden looked at all children listed for heart transplants in the Nordic countries between 1986 and 2023. A total of 597 children were included in the study, 461 of whom received a transplant. The results show that survival rates have increased significantly over time despite the modest volumes in the region – a development that the r

https://www.medicine.lu.se/article/children-waiting-new-heart-study-shows-marked-improvement-survival-rates-and-importance-nordic - 2025-10-29

Hjelt Diabetes Foundation supports research that can pave the way for new cell therapies

Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. The Bo and Kerstin Hjelt Diabetes Foundation provides support to two diabetes researchers at Lund University Diabetes Centre who contribute with new knowledge to this research field. Type 1 diabetes is a condition wh

https://www.medicine.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-10-29

Why repetitive DNA matters for human brain evolution and disease

For decades, large stretches of human DNA were dismissed as ‘junk’ and considered to serve no real purpose. In a new study in Cell Genomics, researchers at Lund University in Sweden show that the repetitive part of the human genome plays an active role during early brain development and may also be relevant for understanding brain diseases. DNA carries the complete set of instructions an organism

https://www.medicine.lu.se/article/why-repetitive-dna-matters-human-brain-evolution-and-disease-0 - 2025-10-29

Scientists uncover cellular “toolkit” to reprogram immune cells for cancer therapy

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialised immune cells. The discovery, published in Immunity, could pave the way for more precise and personalised cancer immunotherapies. The team has taken an important step toward harnessing the immune system to fight cancer. Their work describes how

https://www.medicine.lu.se/article/scientists-uncover-cellular-toolkit-reprogram-immune-cells-cancer-therapy - 2025-10-29

Urine test can assess risk of kidney cancer recurrence

A simple urine test that can assess the risk of kidney cancer recurrence at an early stage could spare patients from frequent imaging scans, e.g. CT-scans, and thus reduce the associated radiation, anxiety and costs. This has been shown in a new international research study led by Lund University in Sweden. The results have now been published in European Urology Oncology. Globally, about 400,000 p

https://www.medicine.lu.se/article/urine-test-can-assess-risk-kidney-cancer-recurrence - 2025-10-29

New global initiative on maternal and newborn health to be led from Sweden

A new international commission will pave the way for a global boost in maternal and newborn health. The project is led by a researcher at Lund University in Sweden, whose motivation stems from a formative experience witnessing a woman bleed to death unnecessarily during childbirth. “The time has come to put maternal and newborn health back at the heart of the global health agenda,” says Mehreen Za

https://www.medicine.lu.se/article/new-global-initiative-maternal-and-newborn-health-be-led - 2025-10-29

ERC grants awarded to research on the interplay between immunology and fertility, and Alzheimer's disease

Congratulations to Jacob Vogel and Camila Consiglio who have been awarded grants to develop their research projects on Alzheimer's and fertility. Camila Consiglio's research focuses on infertility and the immune system that plays a central role in determining reproductive success. Jacob Vogel and his research team will develop computational simulations of Alzheimer’s disease enabling virtual exper

https://www.medicine.lu.se/article/erc-grants-awarded-research-interplay-between-immunology-and-fertility-and-alzheimers-disease - 2025-10-29

Highlights from the Lund Spring Symposium 2025

From Nobel Prizes to visions of the future – over a few days in May, world-leading medical researchers and biotech pioneers gathered to discuss new molecular therapies: from genetic fundamentals to clinical breakthroughs in patients. The program spanned everything from cutting-edge basic science to new treatment principles in drug development. Three intense days marked by curiosity, persistence, a

https://www.medicine.lu.se/article/highlights-lund-spring-symposium-2025 - 2025-10-29

Science, Responsibility and Resilience – A Conversation on the Future of Medicines

At this year’s Lund Spring Symposium, two veteran leaders of pharmaceutical research – Jan M. Lundberg and Mikael Dolsten – engaged in a wide-ranging conversation about scientific courage, setbacks, technological leaps, and hope for the future. The 2025 edition of the symposium, held in May, was filled with highlights. Among them was the thought-provoking exchange between Mikael Dolsten, former Ch

https://www.medicine.lu.se/article/science-responsibility-and-resilience-conversation-future-medicines - 2025-10-29

RNAi: A Genetic Spark in the Information Inferno of the Cell

The information age predates the internet by a long stretch – it began with life itself. Nobel Laureate Craig C. Mello described at the Lund Spring Symposium in May how living organisms are not merely carriers of genes, but also active managers, defenders, and editors of genetic information. Craig Mello, who received the Nobel Prize in 2006 for the discovery of RNA interference (RNAi), together wi

https://www.medicine.lu.se/article/rnai-genetic-spark-information-inferno-cell - 2025-10-29

Rewriting Genetic Fate: Katherine High and the Rise of Gene Therapy

LUND SPRING SYMPOSIUM – When Katherine A. High began working with gene therapy, the field was new, promising – and riddled with uncertainty. Three decades later, she is a visiting professor at The Rockefeller University, CEO of RhyGaze AG, and former President and Head of R&D at Spark Therapeutics. Her research has led to life-changing treatments for patients with inherited diseases. But the road

https://www.medicine.lu.se/article/rewriting-genetic-fate-katherine-high-and-rise-gene-therapy - 2025-10-29

Innovative ideas and pioneering solutions from Lund University celebrated

An innovative IVF test and a methane detector – these are some of the future innovation stars developed at Lund University. They are now being recognised by the University and Sparbanken Skåne. Since its launch in 2017, the Future Innovations Award has recognised ideas that can “change our world for the better”. This year, the awards were worth a total of SEK 800,000.The top prize this year goes t

https://www.medicine.lu.se/article/innovative-ideas-and-pioneering-solutions-lund-university-celebrated - 2025-10-29

Award-winning cancer researcher revolutionises diagnosis and treatment worldwide

Professor Thoas Fioretos is the first recipient of Lunds Innovatörspris (the Lund Innovator Award), a newly established prize that recognises research that has been successfully transformed into innovation with a tangible impact on society and the environment. Fioretos receives the award for his pioneering work in blood cancer research and his ability to translate scientific discoveries into life-

https://www.medicine.lu.se/article/award-winning-cancer-researcher-revolutionises-diagnosis-and-treatment-worldwide - 2025-10-29

New digital cognitive test for diagnosing Alzheimer's disease

Researchers at Lund University in Sweden have developed a digital cognitive test for diagnosing Alzheimer's disease that is intended for use in primary care. “This digital test, which patients perform on their own with minimal involvement from healthcare personnel, improves the primary care physician's ability to determine who should be further examined by blood tests for Alzheimer's pathology ear

https://www.medicine.lu.se/article/new-digital-cognitive-test-diagnosing-alzheimers-disease - 2025-10-29

Largest ever TauPET study of Alzheimer’s deepens understanding of the disease

In a study led by Lund University and the Amsterdam University Medical Center, researchers used PET to analyse aggregates of tau pathology in more than 12,000 people from all over the world. The study – the largest ever of its kind – examines the connection between genetic predisposition, gender and age in relation to tau pathology in Alzheimer’s disease. The study is published in Nature Neuroscie

https://www.medicine.lu.se/article/largest-ever-taupet-study-alzheimers-deepens-understanding-disease - 2025-10-29

From healthy to sick in 3D

This year’s largest grant from the IngaBritt och Arne Lundbergs Forskningsstiftelse goes to Vinay S. Swaminathan at Lund University. He is awarded five million SEK for his research on how healthy breast tissue develops into tumors and spreads. Vinay S. Swaminathan’s research group has developed 3D models that mimics the tumor microenvironment in the laboratory. The technology opens new opportuniti

https://www.medicine.lu.se/article/healthy-sick-3d - 2025-10-29

AI model from Lund University indicates four out of ten breast cancer patients could avoid axillary surgery

A project at Lund University in Sweden has trained an AI model to identify breast cancer patients who could be spared from axillary surgery. The model analyses previously unutilised information in mammograms and pinpoints with high accuracy the individual risk of metastasis in the armpit. A newly completed study shows that the model indicates that just over 40 per cent of today’s axillary surgery

https://www.medicine.lu.se/article/ai-model-lund-university-indicates-four-out-ten-breast-cancer-patients-could-avoid-axillary-surgery - 2025-10-29

Psychedelics in the treatment of anorexia – a new pilot study

Anorexia nervosa is a serious psychiatric disorder for which there are limited treatment options, and it has one of the highest mortality rates of any psychiatric diagnosis. A pilot study is now underway at Lund University in Sweden, where researchers are investigating whether psychedelic drugs have an effect on young patients with the disorder. Ward Five at the adult psychiatric clinic in Lund is

https://www.medicine.lu.se/article/psychedelics-treatment-anorexia-new-pilot-study - 2025-10-29

A detective in the mysterious world of proteins

Gemma Atkinson has been awarded this year’s Eric K. Fernström Prize for particularly promising and successful early-career researchers at Lund University. Her research focuses on bacterial proteins in order to understand the protective mechanisms bacteria use against infecting viruses known as bacteriophages. She received the prize for: Groundbreaking discoveries about the bacterial immune system

https://www.medicine.lu.se/article/detective-mysterious-world-proteins - 2025-10-29