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An epidemiological modelling approach for COVID-19 via data assimilation

The global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation which incorporates new data in real-time through variational data assimilation. We analyze and discuss infection rates in the UK, US and Italy. Read more at https

https://www.lupop.lu.se/article/epidemiological-modelling-approach-covid-19-data-assimilation - 2025-09-05

Toward International Harmonization of Breast Implant Registries: International Collaboration of Breast Registry Activities Global Common Data Set

The Poly Implant Prothèse incident and breast implant-associated anaplastic large cell lymphoma have pointed to the need for uniform registries for breast implants as key features to monitoring the outcomes of breast implant surgeries internationally. The purpose of this study was to identify and harmonize common data elements collected by breast implant registries across the International Collabo

https://www.lupop.lu.se/article/toward-international-harmonization-breast-implant-registries-international-collaboration-breast - 2025-09-05

Transatlantic registries of pancreatic surgery in the United States of America, Germany, the Netherlands, and Sweden: Comparing design, variables, patients, treatment strategies, and outcomes

Registries of pancreatic surgery have become increasingly popular as they facilitate both quality improvement and clinical research. We aimed to compare registries for design, variables collected, patient characteristics, treatment strategies, clinical outcomes, and pathology. Read more at https://www.sciencedirect.com/science/article/pii/S0039606020304554?via%3Dihub

https://www.lupop.lu.se/article/transatlantic-registries-pancreatic-surgery-united-states-america-germany-netherlands-and-sweden - 2025-09-05

Registry-based trials: a potential model for cost savings?

Registry-based trials have emerged as a potentially cost-saving study methodology. Early estimates of cost savings, however, conflated the benefits associated with registry utilisation and those associated with other aspects of pragmatic trial designs, which might not all be as broadly applicable. In this study, we sought to build a practical tool that investigators could use across disciplines to

https://www.lupop.lu.se/article/registry-based-trials-potential-model-cost-savings - 2025-09-05

Webinar 25 september 13:00-14:00, via Zoom

Placing research software into Open Science - Initial results from an RDA Sweden and EOSC Nordic collaboration. The concept of Open Science is mostly focused around Open Data and Open Access for published material, with Open Software usually left in the shadow. But in order to ensure transparent and reproducible science, it is essential that also software used in research be adequately documented,

https://www.lupop.lu.se/article/webinar-25-september-1300-1400-zoom - 2025-09-05

Social class and fertility: A long-run analysis of Southern Sweden, 1922-2015

This paper examines social class differences in fertility, using longitudinal micro-level data for a regional sample in Sweden, 1922-2015. Using discrete-time event history models, we estimated the association between social class and parity-specific duration to next birth, adjusting for household income in separate models. Social class was associated with fertility quite independently from income

https://www.lupop.lu.se/article/social-class-and-fertility-long-run-analysis-southern-sweden-1922-2015 - 2025-09-05

North American COVID-19 ST-Segment-Elevation Myocardial Infarction (NACMI) registry: Rationale, design, and implications

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that causes coronavirus disease 2019 (COVID-19), has resulted in a global pandemic. Patients with cardiovascular risk factors or established cardiovascular disease are more likely to experience severe or critical COVID-19 illness and myocardial injury is a key extra-pulmonary manifestation. Read more at https://ww

https://www.lupop.lu.se/article/north-american-covid-19-st-segment-elevation-myocardial-infarction-nacmi-registry-rationale-design - 2025-09-05

American Heart Association COVID-19 CVD Registry Powered by Get With The Guidelines

In response to the public health emergency created by the coronavirus disease 2019 (COVID-19) pandemic, American Heart Association volunteers and staff aimed to rapidly develop and launch a resource for the medical and research community to expedite scientific advancement through shared learning, quality improvement, and research. In <4 weeks after it was first announced on April 3, 2020, AHA’s CO

https://www.lupop.lu.se/article/american-heart-association-covid-19-cvd-registry-powered-get-guidelines - 2025-09-05

Evaluation of the Use of Cancer Registry Data for Comparative Effectiveness Research

In this comparative effectiveness study, a total of 141 randomized clinical trials referenced in the National Comprehensive Cancer Network Clinical Practice Guidelines for 8 common solid tumor types were identified. Data on participants within the National Cancer Database (NCDB) diagnosed between 2004 and 2014, matching the eligibility criteria of the randomized clinical trial, were obtained. The

https://www.lupop.lu.se/article/evaluation-use-cancer-registry-data-comparative-effectiveness-research - 2025-09-05

Development a national minimum data set for poisoning registry in Iran

In the developing countries with high mortality rates, poisoning is considered to be one of the most common causes of admission to emergency wards. Given the importance of registering data on poisoned patients, it is very important to have a complete poisoning Minimum Data Set (MDS). Therefore, the purpose of this study was to determine an MDS for poisoning registry in Iran. Read more at https://o

https://www.lupop.lu.se/article/development-national-minimum-data-set-poisoning-registry-iran - 2025-09-05

A multinational registry to study the characteristics and outcomes of heart failure patients: The global congestive heart failure (G-CHF) registry

The goal of the global congestive heart failure (G-CHF) registry is to collect comparative international data on heart failure characteristics, management, and outcomes and to better understand the determinants that impact the clinical course of heart failure. Read more at https://www.sciencedirect.com/science/article/abs/pii/S0002870320301800

https://www.lupop.lu.se/article/multinational-registry-study-characteristics-and-outcomes-heart-failure-patients-global-congestive - 2025-09-05

Protocol for the Sri Lankan Cerebral Palsy Register pilot study

Cerebral palsy (CP) describes a heterogeneous group of motor disorders resulting from disturbance in the developing brain. CP occurs in approximately 2.1 per 1000 live births in high-income countries, but in low- and middle-income countries (LMICs) the prevalence and severity of CP may be greater and aetiological risk factors different. In Sri Lanka, a LMIC, there have been no epidemiological stud

https://www.lupop.lu.se/article/protocol-sri-lankan-cerebral-palsy-register-pilot-study - 2025-09-05

Mild to Moderate Cognitive Impairment Does Not Affect the Ability to Self-Report Important Symptoms in Patients With Cancer: A Prospective Longitudinal Multinational Study (EPCCS)

Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. Read more at https://www.sciencedirect.com/science/article/pii/S0885392420301342

https://www.lupop.lu.se/article/mild-moderate-cognitive-impairment-does-not-affect-ability-self-report-important-symptoms-patients - 2025-09-05

Study protocol: effects, costs and distributional impact of digital primary care for infectious diseases—an observational, registry-based study in Sweden

The ability to provide primary care with the help of a digital platform raises both opportunities and risks. While access to primary care improves, overuse of services and medication may occur. The use of digital care technologies is likely to continue to increase and evidence of its effects, costs and distributional impacts is needed to support policy-making. Read more at https://bmjopen.bmj.com/

https://www.lupop.lu.se/article/study-protocol-effects-costs-and-distributional-impact-digital-primary-care-infectious-diseases - 2025-09-05

Were there long-term economic effects of exposure to polio vaccination? An analysis of migrants to Sweden 1946–2003

Recent research showed that exposure to the vaccine against polio in early life had no long-term economic benefits among native Swedes. However, whether this result holds for individuals from other countries remains unexplored. This study explores the relationship between exposure to the vaccine and later-life outcomes, but focuses on individuals who migrated to Sweden (birth cohorts 1946–1971), a

https://www.lupop.lu.se/article/were-there-long-term-economic-effects-exposure-polio-vaccination-analysis-migrants-sweden-1946-2003 - 2025-09-05

Plasma Metabolites Associate with All-Cause Mortality in Individuals with Type 2 Diabetes

Alterations in the human metabolome occur years before clinical manifestation of type 2 diabetes (T2DM). By contrast, there is little knowledge of how metabolite alterations in individuals with diabetes relate to risk of diabetes complications and premature mortality. Metabolite profiling was performed using liquid chromatography-mass spectrometry in 743 participants with T2DM from the population-

https://www.lupop.lu.se/article/plasma-metabolites-associate-all-cause-mortality-individuals-type-2-diabetes - 2025-09-05

Validation of ulcerative colitis and Crohn’s disease and their phenotypes in the Danish National Patient Registry using a population-based cohort

The Danish National Patient Registry (DNPR) has been the source of several epidemiological studies of inflammatory bowel disease (IBD). However, the validation dates back to 1996 and lacks outpatient records and disease classification. The aim of this study was to update the validation and assess the validity and reliability of using the registry in disease classification. Read more at https://www

https://www.lupop.lu.se/article/validation-ulcerative-colitis-and-crohns-disease-and-their-phenotypes-danish-national-patient - 2025-09-05

Parental separation/divorce in childhood and tobacco smoking in adulthood: A population-based study

The aim was to investigate associations between the experience of parental separation/divorce in childhood and tobacco smoking in adulthood, adjusting for economic stress in childhood and adulthood and psychological health (General Health Questionnaire GHQ12). Methods: The 2012 public-health survey in Skåne, southern Sweden, is a cross-sectional postal questionnaire population-based study with 28,

https://www.lupop.lu.se/article/parental-separationdivorce-childhood-and-tobacco-smoking-adulthood-population-based-study - 2025-09-05

Pain and analgaesics in patients with hard-to-heal ulcers: using telemedicine or standard consultations

To compare consultations carried out via video with those performed in person for patients with painful, hard-to-heal ulcers, with a focus on ulcer pain and pain treatment. A further aim was to investigate predictors for pain and pain treatment. Read more at https://www.magonlinelibrary.com/doi/full/10.12968/jowc.2020.29.Sup8.S18

https://www.lupop.lu.se/article/pain-and-analgaesics-patients-hard-heal-ulcers-using-telemedicine-or-standard-consultations - 2025-09-05