Background & Aims: Earlier studies have provided varying risk estimates for lymphoma in patients with inflammatory bowel disease (IBD), but often have been limited by detection biases (especially during the first year of follow-up evaluation), misclassification, and small sample size; and rarely reflect modern-day management of IBD. Methods: We performed a binational register-based cohort stud

Analysis of structures subjected to moving loads is presented. In particular, structural effects due to structure-vehicle interaction are studied. The basic equations of the structure-vehicle system are derived by means of continuum mechanics, the finite element method and multibody dynamics.In order to consider the interaction between structure and vehicle in a straightforward way, a special stru

A constitutive model for concrete is formulated. Tensile fracture is described using a smeared crack approach where the fracrure energy is considered and the shear stiffneess in the cracked region is gradually reduced as crackling develops. Environmentally induced strain due to variation of moisture and temperature is taken into account and may be made dependent on the stress state. Creep is model

We report on the physical-point RBC/UKQCD calculation of the leading isospin-breaking corrections to light-meson leptonic decays. This is highly relevant for future precision tests in the flavour physics sector, in particular the first-row unitarity of the Cabibbo-Kobayashi-Maskawa matrix containing the elements Vus and Vud. The simulations were performed using Domain-Wall fermions for 2 + 1 flavo

Program analysis tools, from simple static semantic analysis by a compiler, to complex dynamic analyses of data flow and security, have become commonplace in modern day programming. Many of the simpler analyses, such as the afore- mentioned compiler checking or linters designed to enforce code style, may even go unnoticed or unconsidered by most users, ubiquitous as they are. Despite this, and des

This thesis is concerned with the finite element analysis of the small-amplitude coupled vibration problem of an acoustic fluid enclosed in a flexible and/or rigid container structure. The governing equations for linear elastic solids and inviscid acoustic fluids are derived by a continuum mechanics approach. Modified equations for an acoustic fluid interpenetrating a rigid incompressible porous m

The brain needs sufficient oxygen in order to function normally. This is achieved by a large vascular capillary network ensuring that oxygen supply meets the changing demand of the brain tissue, especially in situations of hypoxia. Brain capillaries are formed by endothelial cells and perivascular pericytes, whereby pericytes in the brain have a particularly high 1:1 ratio to endothelial cells. Pe

Den ekonomiska och sociala ojämlikheten har ökat väsentligt i Sverige under de senaste decennierna. Detta innebär stora utmaningar för socialtjänsten som möter de grupper som drabbats hårdast av denna utveckling. För att klara dessa utmaningar behöver socialtjänsten utveckla nya strategier som möjliggör hållbara sociala lösningar. I detta arbete kan social mobilisering bli ett viktigt redskap. I k

Regimen i Iran missbrukar diplomatisk infrastruktur i operationer som underminerar internationell säkerhet. Sverige bör noggrant övervaka aktiviteterna vid Irans ambassad på Lidingö och överväga att stänga den helt och hållet. Det skriver Arvin Khoshnood, Irankännare och statsvetare samt Ardavan Khoshnood, docent Lunds universitet.The regime in Iran is abusing diplomatic infrastructure in operations that undermine international security. Sweden should closely monitor the activities at Iran's embassy in Lidingö and consider shutting it down entirely. This is written by Arvin Khoshnood, an Iran expert and political scientist, and Ardavan Khoshnood, an associate professor at Lund University.

Abstract: In order to mimic physical characteristics of solid fat, ethylcellulose (EC) was used as an oleogelator in ice creams made with high oleic sunflower oil (HOSO). The aim was to improve structure of ice cream made with fully liquid vegetable oil by inhibiting droplet coalescence and to enable a colloidal fat network by making the oil droplets solid-like. Two different methods for incorpora

In studies recruited on a voluntary basis, lack of representativity may impair the ability to generalize findings to the target population. Previous studies, primarily based on surveys, have suggested that generalizability may be improved by exploiting data on individuals who agreed to participate only after receiving one or several reminders, as such individuals may be more similar to non-partici

The occurrence of coprostanol in soil, surface, and groundwater has recently been reported in several studies. Coprostanol indicates the presence of feces from mammals. For this reason, it is important to establish adsorption behavior in different kinds of geologic media. To our knowledge, we present for the first-time adsorption behavior of coprostanol in soil, sediment, and sand and an estimatio

Background: Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal expansion of blood stem cells with leukemia-associated mutations—is a novel cardiovascular risk factor. Whether CHIP remains prognostic in individuals with established atherosclerotic cardiovascular disease (ASCVD) is less clear. Objectives: This study tested whether CHIP predicts adverse outcomes in individu

In our meta-study from 2022, “A Literature Review and Meta-Analysis of the Effects of Lockdowns on COVID-19 Mortality – II,” we find that the effect of lockdowns—also referred to as ‘Covid restrictions,’ ‘social distancing measures,’ etc.—on mortality was negligible. The first version of our meta-study received criticism from Banholzer, et al. (2022). The authors raised “concerns regarding the sub

Recent years have seen profound challenges to democracy, including grave populist and autocratic shifts. In the Opinion, the EGE examines how certain configurations of digital technologies can contribute to a weakening of democratic institutions, even if they may not be its sole cause. Among these are the spread of harmful information, an unduly narrow understanding of privacy, algorithmic surveil

Gastric cancer is a dominating cause of cancer-associated mortality with limited therapeutic options. Here, we show that syndecan-4 (SDC4), a transmembrane proteoglycan, is highly expressed in intestinal subtype gastric tumors and that this signature associates with patient poor survival. Further, we mechanistically demonstrate that SDC4 is a master regulator of gastric cancer cell motility and in

The efficiency with which flying animals convert metabolic power to mechanical power dictates an individual's flight behaviour and energy requirements. Despite the significance of this parameter, we lack empirical data on conversion efficiency for most species as in vivo measurements are notoriously difficult to obtain. Furthermore, conversion efficiency is often assumed to be constant across flig