Sökresultat

In the early decades of the 17th century, when the idea of the Swedish colony of New Sweden was conceived and realized, America had a vague place in popular consciousness. Knowledge of the new continent was rather limited, and early Swedish images of it were influenced by tales told by foreign travellers and sailors, by pictorial representations in prints and maps, and by news and reports publishe

The Atlantic world looms large in discussions of how the modern world emerged, and what modernization was about; but there have been calls to engage with these topics from the perspective of ‘margins’. Covering large areas of Fennoscandia, the seventeenth-century Kingdom of Sweden represented a northern end of urban Europe, but also encompassed the mythical Lapland, homeland of the Sámi and of nat

Food encodes social and cultural values and has an important role to play in defining identities. In mixed populations, diet can be used to distinguish between ‘us’ and ‘them’. This study investigates the extent to which the inhabitants of mediaeval Tallinn, an important trading centre, used food to maintain distinct identities. Human skeletal material was selected from four mediaeval cemeteries i

INTRODUCTION: Cardiovascular disease (CVD) is a major cause of death in people aging with spinal cord injury (SCI), and is predominantly caused by atherosclerosis, however, knowledge of atherosclerosis in people with SCI is scarce.OBJECTIVE: To describe coronary and carotid atherosclerosis in middle-aged people with long-term cervical and upper thoracic SCI using coronary computed tomography angio

Approximately 70% of breast cancers express estrogen receptor α (ERα) and depend on this key transcriptional regulator for proliferation and differentiation. While patients with this disease can be treated with targeted antiendocrine agents, drug resistance remains a significant issue, with almost half of patients ultimately relapsing. Elucidating the mechanisms that control ERα function may furth

PURPOSE: Ductal carcinoma in situ (DCIS) patients and their physicians currently face challenging treatment decisions with limited information about the individual's subsequent breast cancer risk or treatment benefit. The DCISionRT biological signature developed in this study provides recurrence risk and predicts radiotherapy (RT) benefit for DCIS patients following breast-conserving surgery (BCS)

Background: Venous thromboembolism (VTE) (pulmonary embolism [PE] or deep venous thrombosis [DVT]) is common during acute COVID-19. Long-term excess risk has not yet been established. Objectives: To study long-term VTE risk after COVID-19. Methods: Swedish citizens aged 18 to 84 years hospitalized and/or testing positive for COVID-19 between January 1, 2020, and September 11, 2021 (exposed), strat

The COVID-19 pandemic has accelerated the digital transformation of Higher Education, necessitating a rapid shift from in-person to remote teaching and learning. This study investigates the experiences of doctoral students in an online Sino-Nordic summer school on aging, implemented during the pandemic. A survey was conducted to collect and analyze data on participants’ experiences and perspective

Alzheimer's disease is a neurodegenerative condition which involves heavy neuronal cell death linked to oligomers formed during the aggregation process of the amyloid β peptide 42 (Aβ42). The aggregation of Aβ42 involves both primary and secondary nucleation. Secondary nucleation dominates the generation of oligomers and involves the formation of new aggregates from monomers on catalytic fibril su

En ökad kunskap och medvetenhet i vården och i samhället om palliativa vårdbehov skulle ge våra medborgare en bättre och tryggare tillvaro i livets slutskede.I den vård som bedrivs när livet närmar sig sitt slut saknas ofta – planering för vården i livets slutskede trots multisjuklighet och hög ålder– brytpunktssamtal eller informerande samtal med närstående – dokumentation av patienters behov, ön

Context. Cool stars, such as M giants, can only be analyzed in the near-infrared (NIR) regime due to the ubiquitous titanium oxide features in optical spectra of stars with Teff<4000 K. In dust-obscured regions, the inner bulge and Galactic center region, the intrinsically bright M giants observed in the NIR are an optimal option for studying stellar abundances and the chemical evolution of stella

Main recommendations: Endoscopic mucosal resection (EMR) is the standard of care for the complete removal of large (≥ 10mm) nonpedunculated colorectal polyps (LNPCPs). Increased detection of LNPCPs owing to screening colonoscopy, plus high observed rates of incomplete resection and need for surgery call for a standardized approach to training in EMR. 1 Trainees in EMR should have achieved basic co

Introduction: Head-to-head evaluation of valoctocogene roxaparvovec, the first gene therapy approved for haemophilia A, with emicizumab is not available. Therefore, phase 3 trial data were indirectly compared. Aim: To compare bleeding rates in trials evaluating 6 × 1013 vg/kg valoctocogene roxaparvovec (GENEr8-1; NCT03370913), 1.5 mg/kg emicizumab dosed every week (HAVEN 3; NCT02847637), and FVIII

We describe glaci-lacustrine sediments buried under thick tills in Folldalen, south-east Norway, a site located close to the former centre of the Scandinavian Ice Sheet. Thus, the location implies that the ice sheet had melted when the sediments were deposited. The exposed ground was occupied by arctic vegetation. The best age estimate from 20 quartz luminescence dates is 55.6 ± 4.6 ka. Due to pos

Företag marknadsför över 200 mjukvaror för artificiell intelligens (AI) inom radiologi.Vårdgivare behöver ha möjlighet till opartisk och kvalitetssäkrad utvärdering.Projektet Validering av AI inom bröst­radio­­­logi (VAI-B) startades för att möta detta behov, initialt inom mammografi­screening.

Smart contracts are programs with data (mutable state); stored on and executed by blockchain platforms. The transactions (or function invocations) dispatched to smart contracts often change their state. In the Ethereum blockchain, nodes (aka miners/validators) can schedule a set of transactions in any order in a block. Multiple transactions in a single block operating on a contract's shared state