Vascular complications are common in diabetes. IGF-I receptors (IGF-IR) and insulin receptors (IR) in endothelial cells might respond to altered levels of IGF-I and insulin, resulting in altered endothelial function in diabetes. We therefore studied IGF-IR and IR gene expression, ligand binding, receptor protein, and phosphorylation in human umbilical vein endothelial cells (HUVEC). IGF-IR mRNA wa

In this article it is shown how the tuning of a loop is used to commission a closed-loop performance monitoring method. The extended prediction horizon index is used to monitor disturbance rejection properties expressed with the impulse response. The impulse response is obtained from the tuning of the loop. All parameters of the monitoring method are set by using the impulse response. The presente

Using perturbation facilitated infrared-infrared double resonance excitation of the Rb-85(2) molecule, we have observed spectrally resolved fluorescence to the a (3)Sigma(+)(u) state. We have analyzed the rovibrational energy level structure of the Rb-85(2) a (3)Sigma(+)(u) state and derived a multiparameter Morse Long Range (MLR) potential and molecular constants for this state, which can be used

The hottest developments in the fields of cancer research, neuroscience, genomics and proteomics, anti-virals and more, with a pick of the key research papers in these areas.

We present Auger spectroscopy studies of large krypton clusters excited by soft x-ray photons with energies on and just above the 3d(5/2) ionization threshold. The deexcitation spectra contain new features as compared to the spectra measured both below and far above threshold. Possible origins of these extra features, which stay at constant kinetic energies, are discussed: (1) normal Auger process

Excited states in neutron-deficient mass A similar to 60 nuclei were studied by means of several heavy-ion fusion-evaporation reactions. The G(AMMASPHERE) array in conjunction with ancillary detector systems such as MICROBALL and neutron detectors allowed for the identification of well deformed rotational structures in the second well of nuclei in the direct vicinity of the doubly-magic isotope Ni

The eastern Baltic cod fishery, as many fisheries worldwide, is experiencing a major crisis. The combination of current environmental conditions, fishing mortality rates, and stock size indicates that this fishery is not sustainable. In order to rebuild the population and sustain the fishery in the future, it is essential to define a biologically appropriate exploitation level. In this paper, we t

A strictly anaerobic, mesophilic, endospore-forming, lipolytic bacterium, designated strain R1(T), was isolated from bovine rumen fluid and characterized. Cells of this isolate were Gram-positive, non-motile rods that formed spherical terminal spores. The overall biochemical and physiological characteristics indicated that this strain should be placed in the genus Clostridium. The strain grew at t

The influence of pH on the growth and assimilation of N-15-labelled ammonium and nitrate was studied in intact ectomycorrhizal systems consisting of Betula pendula Roth and Picea abies (L.) Karst. colonized with a common mycelium of Paxillus involutus (Batsch) Fr. The plants were grown together in Plexiglass observation chambers containing non-sterile peat with three different pH values, 4.0, 5.1

Differentiation of multipotent mesenchymal stem cells into lipid-accumulating adipocytes is a physiological process induced by transcription factors in combination with hormonal stimulation. We have used Affymetrix microarrays to compare the adipogenic differentiation pathways of NIH-3T3 fibroblasts induced to undergo in vitro differentiation by ectopic expression of early B cell factor (EBF)-1 or

Abstract in UndeterminedAims: To examine how left atrioventricular plane displacement ( AVPD), a widely used measure of left ventricular (LV) function, is related to presence and degree of aortic stenosis. Methods and results: Cardiac dimensions, LV filling, left AVPD, LV ejection fraction (LVEF), and valve function were assessed by echocardiography/Doppler in 182 patients with various cardiac dis

Results of the Jefferson Lab Hall A quasielastic 3He(e,ep)pn measurements are presented. These measurements were performed at fixed transferred momentum and energy, q=1502 MeV/c and =840 MeV, respectively, for missing momenta pm up to 1 GeV/c and missing energies in the continuum region, up to pion threshold; this kinematic coverage is much more extensive than that of any previous experiment. The

We present a formalism which modifies the Mueller Dipole Model such that it incorporates energy-momentum conservation as well as important colour suppressed effects in the cascade evolution. The formalism is implemented in a Monte Carlo simulation program, and the results are compared to inclusive data from HERA and the Tevatron. We here find a generally very good agreement between our model and t

Ethylhydroxyethyl cellulose (EHEC) of three different viscosity classes (EHEC I, II, and III) was analyzed by programmed cross-flow asymmetrical flow field-flow fractionation coupled to multiangle light scattering and refractive index detectors to determine their size and molar mass distribution. Two size populations were detected in the two lower viscosity classes, EHEC I and II, one high molar m

The level of host specificity of blood-sucking invertebrates may have both ecological and evolutionary implications for the parasites they are transmitting. We used blood meals from wild-caught blackflies for molecular identification of parasites and hosts to examine patterns of host specificity and how these may affect the transmission of avian blood parasites of the genus Leucocytozoon. We found

Objective. C1q deficiency is the strongest risk factor known for the development of systemic lupus erythematosus (SLE), since almost all humans with a genetic deficiency of C1q develop this disease. Low C1q serum concentration is also a typical finding in SLE during flares, emphasizing the involvement of C1q in SLE pathogenesis. Recent studies have revealed that C1q has a regulatory effect on Toll

Self-incompatibility (SI) in plants is a classic example of a trait evolving under strong frequency-dependent selection. As a consequence, population genetic theory predicts that the S locus, which controls SI, should maintain numerous alleles, display a high level of nucleotide diversity, and, in structured populations, show a lower level of among-population differentiation compared to neutral lo