The crystalline lens of the vertebrate eye grows throughout life. This growth may be enormous in fish, while the lens must be functional from larva to adult. During growth, the fiber cells of the lens must increase the concentration of specific proteins (crystallins) in the cytoplasm to increase refractive index. However, the bulk of the fiber cells in a vertebrate lens are denucleated and have no

Report for Tillväxtverket – the Swedish Agency for Economic and Regional Growth.

A key assumption conventionally made by flexible head-mounted eye-tracking systems is often invalid: The eye center does not remain stationary w.r.t. the eye camera due to slippage. For instance, eye-tracker slippage might happen due to head acceleration or explicit adjustments by the user. As a result, gaze estimation accuracy can be significantly reduced. In this work, we propose Grip, a novel g

Det småskaliga fisket längs Östersjökusten minskar idag i snabb takt. Det finns mångamöjliga orsaker till utvecklingen. En som uppmärksammats är de växande sälstammarna i Östersjön eftersom de konkurrerar med människan om fiskresursen. Både det kustnära fisket och sälen är viktiga delar av Östersjöns kultur- och naturliv, men de senasteårens utveckling tyder på att det är svårt för småskaligt fisk

Under the Sign of Regret focuses on aesthetically mediated responses to regret. It interrogates the qualities of the feeling of regret as well as what is produced under its influence (as objects and as experiences). These two aims—considering regret as a mode and as a tool—hinge between two complementary definitions of aesthetics: on the one hand, the quality of feelings or the “distribution of th

Asymmetric flow field-flow fractionation (AF4) is a separation technique in which a focusing/relaxation step is used after the sample is injected onto the separation channel. During the focusing/relaxation step, the sample is focused by two counter-directed flows. This allows sample components to establish a diffusion-dependent equilibrium concentration profile. The focusing step may, in some case

Background: Genome-wide association studies (GWAS) have identified >50 single nucleotide polymorphisms (SNP) in association with estimated glomerular filtration rate (eGFR) and chronic kidney disease (CKD) but little is known about whether the combination of these SNPs may aid in prediction of future incidence of CKD in the population. Methods: We included 2301 participants with baseline eGFR ≥60

With advancing age, changes in the arterial wall contribute to what has been called vascular aging, and in some prematurely affected subjects even early vascular aging (EVA).1–5 Several years ago,1 we listed various components of EVA, including arteriosclerosis, atherosclerosis, and excess vasoconstriction, with their clinical expression: arterial stiffening and increased central pulse pressure, c

The aim of this article was to investigate presentations of “wet” eldercare facilities in Sweden, a type of facility that provides care for older people with long-term alcohol problems and where the consumption of alcohol is allowed. Wet eldercare facilities challenge traditional Swedish policy on alcohol treatment, and their approach constitutes a breach of mainstream policies on alcohol and trea

For a better understanding of possible physical links between geophysical observables and earthquake characteristics, it is important to analyze statistical spatiotemporal patterns in nature related to such events. For this purpose, characteristic changes in groundwater level (GWL) were observed before and after the 2016 Kumamoto earthquake in Japan. Previous research has shown that self-organizin

The performance of baseband beamforming in multi-user multiple-input multiple-output (MU-MIMO) systems has been extensively studied for simplified statistical channel models where no angular parameters are taken into account. In contrast, there is little performance analysis with ray-based models, which are more physically motivated, feature prominently in standardization and have been experimenta

https://www.schirn.de/en/magazine/interviews/2018_interview/interview_joachim_koester/

AIM: The aim of this study was to assess the predictive role of biomarkers, associated with cardiovascular stress and its neuroendocrine response as well as renal function, in relation to mortality and risk of re-hospitalization among consecutive patients admitted because of heart failure (HF).METHODS AND RESULTS: A total of 286 patients (mean age, 75 years; 29% women) hospitalized for newly diagn

Little attention has been given to the design of efficient studies to evaluate longitudinal biomarkers. Measuring longitudinal markers on an entire cohort is cost prohibitive and, especially for rare outcomes such as cancer, may be infeasible. Thus, methods for evaluation of longitudinal biomarkers using efficient and cost-effective study designs are needed. Case cohort (CCH) and nested case-contr

We propose and study a fully efficient method to estimate associations of an exposure with disease incidence when both, incident cases and prevalent cases, i.e., individuals who were diagnosed with the disease at some prior time point and are alive at the time of sampling, are included in a case-control study. We extend the exponential tilting model for the relationship between exposure and case s

Motivation: Comparisons of microbiome communities across populations are often based on pairwise distance measures (beta-diversity). Standard analyses (principal coordinate plots, permutation tests, kernel methods) require access to primary data if another investigator wants to add or compare independent data. We propose using standard reference measurements to simplify microbiome beta-diversity a