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Open Science—A Question of Trust

Collaboration and the sharing of knowledge is at the heart of Open Science (OS). However, we need to know that the knowledge we find and share is really what it purports to be; and we need to know that the authors we hope to collaborate with are really the people they claim to be. Read the paper at https://direct.mit.edu/dint/article/3/1/64/94911/Open-Science-A-Questio…

https://www.lupop.lu.se/article/open-science-question-trust - 2025-10-21

Generalizability of Subgroup Effects

Generalizability methods are increasingly used to make inferences about the effect of interventions in target populations using a study sample. Most existing methods to generalize effects from sample to population rely on the assumption that subgroup-specific effects generalize directly. However, researchers may be concerned that in fact subgroup-specific effects differ between sample and populati

https://www.lupop.lu.se/article/generalizability-subgroup-effects - 2025-10-21

Pregnancy intention data completeness, quality and utility in population-based surveys

An estimated 40% of pregnancies globally are unintended. Measurement of pregnancy intention in low- and middle-income countries relies heavily on surveys, notably Demographic and Health Surveys (DHS), yet few studies have evaluated survey questions. Read the paper at https://pophealthmetrics.biomedcentral.com/articles/10.1186/s12963-020-…

https://www.lupop.lu.se/article/pregnancy-intention-data-completeness-quality-and-utility-population-based-surveys - 2025-10-21

Redesign of the Australian Cystic Fibrosis Data Registry: A multidisciplinary collaboration

Clinical registries that monitor and review outcomes for patients with cystic fibrosis have existed internationally for many decades. However, their purpose continues to evolve and now includes the capability to support clinical effectiveness research, clinical trials and Phase IV studies, and international data comparisons and projects. Read the paper at https://www.sciencedirect.com/science/arti

https://www.lupop.lu.se/article/redesign-australian-cystic-fibrosis-data-registry-multidisciplinary-collaboration - 2025-10-21

The European Paediatric Rare Tumours Network - European Registry (PARTNER) project for very rare tumors in children

The PARTNER project (Paediatric Rare Tumours Network - European Registry) was launched in 2016. PARTNER aims to create a European Registry dedicated to children and adolescents with very rare tumors (VRT). It links existing national registries and provides a registry for those countries in which a VRT registry has not yet been created. Read the paper at https://onlinelibrary.wiley.com/doi/full/10.

https://www.lupop.lu.se/article/european-paediatric-rare-tumours-network-european-registry-partner-project-very-rare-tumors-children - 2025-10-21

Complex systems models for causal inference in social epidemiology

Systems models, which by design aim to capture multi-level complexity, are a natural choice of tool for bridging the divide between social epidemiology and causal inference. In this commentary, we discuss the potential uses of complex systems models for improving our understanding of quantitative causal effects in social epidemiology. Read the essay at http://dx.doi.org/10.1136/jech-2019-213052

https://www.lupop.lu.se/article/complex-systems-models-causal-inference-social-epidemiology - 2025-10-21

Assessing knowledge, attitudes, and practices towards causal directed acyclic graphs: a qualitative research project

We sought to understand why researchers do or do not regularly use DAGs by surveying practicing epidemiologists and medical researchers on their knowledge, level of interest, attitudes, and practices towards the use of causal graphs in applied epidemiology and health research. Read the paper at https://link.springer.com/article/10.1007%2Fs10654-021-00771-3

https://www.lupop.lu.se/article/assessing-knowledge-attitudes-and-practices-towards-causal-directed-acyclic-graphs-qualitative - 2025-10-21

Assessing the external validity of the VALIDATE-SWEDEHEART trial

The VALIDATE-SWEDEHEART trial was a registry-based randomized trial comparing bivalirudin and heparin in patients with acute myocardial infarction undergoing percutaneous coronary intervention. It showed no differences in mortality at 30 or 180 days. This study examines how well the trial population results may generalize to the population of all screened patients with fulfilled inclusion criteria

https://www.lupop.lu.se/article/assessing-external-validity-validate-swedeheart-trial - 2025-10-21

Estimating perceived parental substance use disorder: Using register data to adjust for non-participation in survey research

Aims: To estimate the prevalence of parental substance use disorder (PSUD) in the general population based on young adults' reports adjusted for non-participation using register-based indicators of PSUD. Read the paper at https://europepmc.org/article/med/33878599

https://www.lupop.lu.se/article/estimating-perceived-parental-substance-use-disorder-using-register-data-adjust-non-participation - 2025-10-21

Integrating data from multiple Finnish biobanks and national health-care registers for retrospective studies: Practical experiences

A large cohort, consisting of versatile individual-level phenotype and genotype data, can be constructed by integrating data from several biobanks and health data registers in Finland. Co-operation with biobanks is straightforward. However, long time periods need to be reserved when biobank resources are linked with national register data. Read the paper at https://journals.sagepub.com/doi/full/10

https://www.lupop.lu.se/article/integrating-data-multiple-finnish-biobanks-and-national-health-care-registers-retrospective-studies - 2025-10-21

How to design a registry for undiagnosed patients in the framework of rare disease diagnosis: suggestions on software, data set and coding system

About 30 million people in the EU and USA, respectively, suffer from a rare disease. Driven by European legislative requirements, national strategies for the improvement of care in rare diseases are being developed. Read the paper at https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-01831-3

https://www.lupop.lu.se/article/how-design-registry-undiagnosed-patients-framework-rare-disease-diagnosis-suggestions-software-data - 2025-10-21

A Canadian Prospective Study of Linkage of Randomized Clinical Trial to Cancer and Mortality Registry Data

In a prospective study, we sought to determine acceptability of linkage of administrative and clinical trial data among Canadian patients and Research Ethics Boards (REBs). The goal is to develop a more harmonized approach to data, with potential to improve clinical trial conduct through enhanced data quality collected at reduced cost and inconvenience for patients. Read the paper at https://www.n

https://www.lupop.lu.se/article/canadian-prospective-study-linkage-randomized-clinical-trial-cancer-and-mortality-registry-data - 2025-10-21

Umeå universitet söker forskningssamordnare med fokus på processer för biobankers forskningsdata

Du kommer att samla in och ställa samman kunskap om forskningsdata och dess hantering i biobankskohorter, såväl i Umeå som nationellt. Målet är att peka ut förbättringsområden, för förbättrade och förenklade flöden för forskningen. Parallellt kommer du att arbeta med att ge konkret stöd till forskare inom olika biobanksprojekt. Läs mer och ansök på https://www.umu.se/jobba-hos-oss/lediga-jobb/fors

https://www.lupop.lu.se/article/umea-universitet-soker-forskningssamordnare-med-fokus-pa-processer-biobankers-forskningsdata - 2025-10-21

Ny studie: Maskininlärning för bättre diagnostik och behandling av vuxna patienter som söker sjukvård på grund av andningssvårigheter

Vi avser i detta projekt undersöka om vi med maskininlärning (artificiell intelligens, AI) kan träna en dator att känna igen mönster i akutpatienters data, såsom tidigare sjukdomar, läkemedelsanvändning, undersökningsresultat och sociala faktorer, för att sedan kunna förutsäga vilken eller vilka av de vanligaste sjukdomarna patienten har, som orsakar andningssvårigheterna. Syftet är att patienter

https://www.lupop.lu.se/article/ny-studie-maskininlarning-battre-diagnostik-och-behandling-av-vuxna-patienter-som-soker-sjukvard-pa - 2025-10-21

New position as assistant researcher in epidemiology

We are looking for an assistant researcher in Epidemiology for work that is linked to a thematic collaborative initiative on improved pandemic preparedness that has received internal funding from Lund University 2021 – 2024. The initiative is a truly interdisciplinary collaboration for research and infrastructure development that involves Lund university, Umeå university, Halmstad university, Regi

https://www.lupop.lu.se/article/new-position-assistant-researcher-epidemiology - 2025-10-21