Tracer kinetic modeling for quantification of perfusion and capillary wall permeability is a well-established approach, applied to various imaging modalities. In this review, methods employing intravascular as well as diffusible nonradioactive contrast agents for characterization of tissue microcirculation and microvasculature are described. The article focuses on perfusion and permeability imagin

Paperboard mechanical properties at fracture during uniaxial tests is an interplay between available elastic energy at fracture and the fracture energy needed to separate the sample into two parts. A test at a critical length, the load vs. elongation curve immediately falls from a point of instability to zero load. Whereas, a test at a stable length give a stable descending load-elongation curve wPaperboard mechanical properties at fracture during uniaxial tests is an interplay between available elastic energy at fracture and the fracture energy needed to separate the sample into two parts. In a test at a critical specimen length, the load vs. elongation curve immediately drops from a point of instability to zero load, whereas a test at a stable length gives a stable descending load-elonga

Some years ago it was decided that a European curriculum should be developed for medical physicists professionally engaged in the support of clinical diagnostic imaging departments. With this in mind, EFOMP (European Federation of Organisations for Medical Physics) in association with ESR (European Society of Radiology) nominated an expert working group. This curriculum is now to hand. The curricu

We have examined the binding of [3H]bradykinin to bovine myometrial membranes and assessed its sensitivity to guanine nucleotides. Total binding displayed a typical B2 kinin receptor specificity. However, saturation binding isotherms were resolved into at least two components with K(D) values of 8 pM (45%) and 378 pM (55%). Low affinity binding exhibited relatively rapid rates of association (k(ob

Desensitization of the β-adrenergic receptor, a receptor which is coupled to the stimulation of adenylate cyclase, may be regulated via phosphorylation by a unique protein kinase. This recently discovered enzyme, known as the β-adrenergic receptor kinase, only phosphorylates the agonist-occupied form of the β-adrenergic receptor. To assess whether receptors coupled to the inhibition of adenylate c

Continuous exposure of DDT1 MF-2 smooth muscle cells to 10-100 μM norepinephrine results in a dramatic attenuation of the ability of norepinephrine to stimulate inositol phospholipid hydrolysis via α1-adrenergic receptors (α1-AR). In addition to the functional desensitization, norepinephrine exposure also reduces the number of accessible cell surface α1-AR as assayed by [3H]prazosin binding at 4°

This study explored the effects of adding visual continuous feedback in the form of feedback bars to a teachable-agent based learning game in mathematics. Forty-five (45) children, 8- to 12-years-old, from three Swedish school classes used the game during four math lessons. The focus was on how feedback to the students regarding their teachable agents learning progression - and different detailed

Skriften beskriver hur våldsbejakande högerextremism ser ut i det samtida Sverige. Författaren gör en historisk tillbakablick, belyser internationella kopplingar, symboler och idéer. Inom nationalistiska ideologier har det länge funnits idealbilder om hur män och kvinnor ska vara. Kärnfamiljens betydelse betonas och att uppfostra nationens barn har betraktats som viktigt för att nationen ska överl