Search results

Objective: Non-coding RNAs constitute a major fraction of the β-cell transcriptome. While the involvement of microRNAs is well established, the contribution of long non-coding RNAs (lncRNAs) in the regulation of β-cell functions and in diabetes development remains poorly understood. The aim of this study was to identify novel islet lncRNAs differently expressed in type 2 diabetes models and to inv

QmeQ is an open-source Python package for numerical modeling of transport through quantum dot devices with strong electron-electron interactions using various approximate master equation approaches. The package provides a framework for calculating stationary particle or energy currents driven by differences in chemical potentials or temperatures between the leads which are tunnel coupled to the qu

Världens befolkning ökar och i takt med det utbredningen av städer och urbana miljöer. Urbaniseringen är en extrem utmaning för många djurarter och antalet arter har minskat i takt med urbaniseringen. Trots detta finns det en hel del arter som tillsynes verkar blomstra i staden, mycket tack vara den rika tillgången till mat. Men så finns det en också baksida, nämligen de olika miljöföreningar som Urbanisation of natural habitats is rapidly intensifying and poses a potential global threat for wildlife. Thus, it is important to explore its impact on wildlife in order to understand the present and future threats and how resilient organisms are to them. Although many species decline in abundance or even disappear once an area is urbanised, some species, populations and/or individuals are able

The interaction between the renal water channel aquaporin-2 (AQP2) and the lysosomal trafficking regulator-interacting protein LIP5 targets AQP2 to multivesicular bodies and facilitates lysosomal degradation. This interaction is part of a process that controls AQP2 apical membrane abundance in a vasopressin-dependent manner, allowing for urine volume adjustment. Vasopressin regulates phosphorylati

Since the last decade, development efforts by academia and industry for automated driving functions have increased significantly. Also, the European research project AdaptIVe is looking into this topic. Due to the large operation spaces and various complex situations that are covered by these functions, efforts for evaluation increase also significantly. Within AdaptIVe, a comprehensive evaluation

The ability to inhibit unproductive motor responses triggered by salient stimuli is a fundamental inhibitory skill. Such motor self-regulation is thought to underlie more complex cognitive mechanisms, like self- control. Recently, a large-scale study, comparing 36 species, found that absolute brain size best predicted competence in motor inhibition, with great apes as the best performers. This was

Objectives: The symptoms of Posttraumatic Stress Disorder (PTSD) and chronic pain are thought to interact to increase the severity and impact of both conditions, but the mechanisms by which they interact remain unclear. This study examines the relationship between PTSD and chronic pain and whether indices of psychological flexibility mediate the relationship between these two conditions.Methods: S

Pricing carbon is often considered to be the cornerstone of any climate policy and, at least in economic theory, it is the only policy intervention required to reach an optimal level of mitigation. In practice, various market and behavioural failures, as well as political barriers, necessitate a policy mix that also encompasses policies to induce energy efficiency and stimulate the up-take of rene

Presenterar Crusenstolpes erfarenheter av Lund och Lunds universitet med fokus på hans samtidsroman Tvenne äktenskap (1847).

Presenterar Wranérs studietid i Lund och lundabilden i hans folklivsskildringar.

Porträtterar Nils Ludvig som dialektpoet, lundaskildrare och folkbildare.

Titan, Demon and Genius in the Poetical Work of Mihai Eminescu is a book that furthers on the interpretation of the most representative Eminescu’s poems and also of his lyrical theatre. Besides, a special chapter is dedicated to the cultural context of the second half of the 19th century and another one records the literary works inspired by Eminescu’s works and personality throughout the 20th cen

This study is considering turbocharger turbine performance at "on-engine" conditions with respect to turbine design variables and exhaust manifold volume. The highly unsteady nature of the internal combustion engine will result in a very wide range of turbine operation, far from steady flow conditions. As most turbomachinery design work is conducted at steady state, the influence of the chosen tur

Solvent effects on the decomposition of formic acid over a Co(111) surface were studied via density functional theory calculations combined with a continuum implicit solvation model. The solvents used here were water, methanol, and acetone. The adsorption energies of key intermediates, the activation barriers and the rate and equilibrium constants of various elementary reactions in vacuum and in t

In this letter, the fading statistics of wireless channels in high-speed railway cutting scenarios are characterized based on measurements. A multiple scattering model called second-order scattering fading (SOSF) is used to model the small-scale fading considering the influence of cuttings and bridges. The SOSF model can offer the possibility of analytical estimation for different fading severitie

The paper describes a multidisciplinary conceptual design of an axial compressor, targeting a three stage, high speed, high efficiency booster with a design pressure ratio of 2.8. The paper is outlined in a step wise manner starting from basic aircraft and engine thrust requirements, establishing the definition of the high speed booster interface points and its location in the engine. Thereafter,

Thin Co films intercalated between a Graphene capping layer and the Ir(111) surface are of interest for spintronics applications due to their peculiar magnetic properties and to their chemical stability. The structure, and then the magnetic properties, of the Co films depend on the intercalation process which is strongly influenced by the temperature, total amount of Cobalt and quality of the capp

This work deals with analysis and modelling of the radionuclides 210Pb and210Po in the food-chain lichen-reindeer-man in addition to 210Po and 137Cs in top predators. By using the methods of Partial Least Square Regression (PLSR) the atmospheric deposition of 210Pb and 210Po is predicted at the sample locations. Dynamic modelling of the activity concentration with differential equations is fitted

A pocket cavity is generated at the connection of two parts, such as the transition part between the low pressure turbine (LPT) and outlet guide vane (OGV) in a gas turbine engine. A bluff body, working as a heat transfer enhancement part or supporting strength part, has tremendous engineering applications in turbomachinery. In the present work, the effect of the pocket on the heat transfer of end