Foto: iStock/kali9 There were no differences in quality of life, symptoms, hospital admissions or mortality between a group of patients with pulmonary disease and low oxygen levels in the blood that received oxygen therapy at home for 24 hours a day, and a group that received the same therapy for 15 hours a day, according to a study from Lund University in Sweden. “This has considerable significan

https://www.medicine.lu.se/article/no-benefits-24-hour-compared-15-hour-oxygen-therapy - 2025-08-21

Researchers are developing a new cancer immunotherapy that reprograms cancer cells into dendritic cells using an adenoviral vector. The image shows how this new approach, tested In preclinical studies, works. Image credit: Joana Carvalho. Researchers at Lund University are developing a new type of gene therapy that reprograms cancer cells within tumors into immune cells that can help the immune sy

https://www.medicine.lu.se/article/researchers-reprogram-tumor-cells-cancer-fighting-immune-cells-living-beings - 2025-08-21

PhD student Luís Oliveira drew resounding applause for his presentation on how he reprograms cancer cells. Photo: Bodil Malmström. By describing his research as a battle between good and evil and likening himself to a hacker who attacks cancer cells to make them kind, PhD student Luís Oliveira took home the win in this year's Research Grand Prix. It is a competition in presentation technique for r

https://www.medicine.lu.se/article/he-won-regional-heat-researcher-grand-prix-now-heading-national-contest-stockholm - 2025-08-21

Aleksander Giwercman and Amelie Stenqvist (Photo: Åsa Hansdotter) For the first time, researchers have linked specific frequent defects in sperm to risk of pregnancy complications and negative impacts on the health of the baby. The study from Lund University in Sweden shows that high proportion of father’s spermatozoa possessing DNA strand breaks is associated with doubled risk of preeclampsia in

https://www.medicine.lu.se/article/defective-sperm-doubles-risk-preeclampsia - 2025-08-21

Men produce hundreds of millions of sperm every day, which means that the male germ cells are constantly undergoing cell division, increasing the risk of harmful mutations.Photo: iStock/Shidlovski It has previously been difficult to identify DNA mutations in sperm, as these changes are rare, and most sequencing techniques have a large margin of error. Now a research study led from Lund University,

https://www.medicine.lu.se/article/new-method-enables-identification-mutations-sperm - 2025-08-21

Kári Stefánsson, Professor at the University of Iceland and CEO of deCODE genetics, has been awarded the Eric K. Fernström foundation Grand Nordic Prize, Lund University. Photo: JG/deCODE genetics A career in science was not on the map for Kári Stefánsson, who aspired to become a writer. But life took another road and the return to Iceland almost three decades ago marked the start of a journey tha

https://www.medicine.lu.se/article/success-makes-it-difficult-quit - 2025-08-21

Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. Photo: iStock/Suriyawut Suriya Obesity is a common cause of diabetes, heart disease and early death, but risk differs greatly from one person to the next. In work led by researchers at Lund University in Sweden as part of the Innovative Medicine Initiative project SOPHIA, a p

https://www.medicine.lu.se/article/new-precision-medicine-approach-helps-detect-subgroups-people-obesity-high-risk-diabetes-and-heart - 2025-08-21

Joao Duarte's research group is investigating how the brain is affected by diabetes. Photograph: Petra Olsson Diabetes researcher Joao Duarte specialices in studying what happens in the brain in diabetes. In his research, he is also investigating how diet changes can improve brain function in connection with diabetes. He will be awarded this year's Medeon stipend on the World Diabetes Day Skåne ev

https://www.medicine.lu.se/article/praised-research-diabetes-and-dementia - 2025-08-21

Research nurse Jessica Melin takes a blood sample from a study participant. In the film Åke Lernmark, principal investigator of the TEDDY study in Sweden, explains the most important results of the TEDDY-study. In 2025, children within the TEDDY study will submit their final samples at research clinics in Sweden, Finland, Germany and the United States. The international study has provided a lot of

https://www.medicine.lu.se/article/new-knowledge-about-type-1-diabetes-large-scale-teddy-study-will-soon-be-completed - 2025-08-21

“Our goal is to make advances in stem cell therapy by modifying and adapting cells to the patient’s needs", explains Malin Parmar. Photo: Tove Smeds. Malin Parmar, professor of cellular neuroscience, along with three researchers in Italy and Denmark, has been awarded the prestigious ERC Synergy Grant worth EUR 10 million. The four researchers aim to develop custom-made neurons from stem cells for

https://www.medicine.lu.se/article/erc-synergy-grant-awarded-development-custom-made-stem-cell-therapies - 2025-08-21

Foam cells visualised using confocal microscopy in tissue from a glioblastoma patient: the nucleus (blue), a marker for macrophages that are recruited from the bone marrow (green) and lipid droplets that gave the foam cell its name. Credit: Governa et al A research team at Lund University in Sweden has discovered a certain type of cells – foam cells – in patients with the aggressive brain tumour g

https://www.medicine.lu.se/article/foam-cells-brain-tumours - 2025-08-21

Johan Flygare and the remarkable story of the genesis of Apriligen, a company which aims to find a cure for the rare blood disease, Diamond–Blackfan Anemia, DBA. Photo: Johan Persson. After 20 years of research on gene therapy and the rare blood disease, Diamond-Blackfan Anemia, DBA, researcher Johan Flygare had reached a point where he and his colleagues had done everything they could in the lab.

https://www.medicine.lu.se/article/science-start-developing-gene-therapy-rare-blood-disorder - 2025-08-21

In a study published in Advanced Science, researcher Fredrik Ek et al. describe how they can use light to create electrically conductive materials directly in the body, showing promising results in animal trials. Photo: I. Hultquist. Bioelectronics research and development of implants made of electrically conductive materials for disease treatment is advancing rapidly. However, bioelectronic treat

https://www.medicine.lu.se/article/using-light-create-bioelectronics-inside-body - 2025-08-21

Kristian Riesbeck, professor of clinical bacteriology at Lund University. Photo: Tove Smeds It has been a year ago since bacteria from war-wounded at hospitals in Ukraine were analysed. The study, which attracted a lot of attention, showed that some of the bacteria types had total resistance to antibiotics. Now, the same researchers have examined the infectiousness of the bacteria. "The bacterium

https://www.medicine.lu.se/article/pandrug-resistant-bacteria-war-ukraine-are-extremely-pathogenic - 2025-08-21

Magnesium plays a crucial role in protecting cells against damage from free radicals (antioxidant defense). Illustration: iStock/Just_Super An international team of researchers, led by scientists at Lund University, has uncovered how magnesium enters mitochondria. Magnesium is a vital mineral that plays a key role in numerous biological processes in the body. Among other functions, it is crucial f

https://www.medicine.lu.se/article/auto-regulating-channels-supply-our-cells-magnesium - 2025-08-21

"This collaboration is truly valuable and with high potential because it merges clinical, molecular, and computational expertise,” states Johan Jakobsson. Photo: iStock/Vitalii Gulenok A team of international researchers led by Professor Johan Jakobsson at Lund University has secured a 52 million SEK grant from the Aligning Science Across Parkinson’s (ASAP) initiative, in partnership with the Mich

https://www.medicine.lu.se/article/52-million-sek-goes-uncovering-genetic-drivers-parkinsons-disease-0 - 2025-08-21

Isabel Gonçalves and Andreas Edsfeldt have analysed atherosclerotic plaques from patients who have type 2 diabetes and patients who do not have the disease. Photo: Petra Olsson People with type 2 diabetes have a higher risk of developing cardiovascular disease and dying prematurely due to atherosclerosis. A research team at Lund University in Sweden has now identified molecular mechanisms that may

https://www.medicine.lu.se/article/new-explanation-dangerous-atherosclerotic-plaques-type-2-diabetes - 2025-08-21

The study shows that intake of sweetened beverages showed stronger links to cardiovascular disease than any other form of sugar. Photo: Unsplash/Megan Watson An observational study from Lund University in Sweden examining sugar consumption has attracted considerable international attention. The study shows that sweetened beverages have a greater negative impact on health than other sources of suga

https://www.medicine.lu.se/article/questions-and-answers-lund-university-sugar-study - 2025-08-21

Nicholas Leigh is a senior lecturer and researcher in regenerative immunology. In Sweden, only a few research groups in the field study salamanders. Photo: Åsa Hansdotter Nicholas Leigh came from the United States to Sweden and Lund University four years ago. In his research, he focuses on salamanders and how they can recreate body parts such as legs, tails and even components of the heart. It was

https://www.medicine.lu.se/article/seeking-shutdown-button-cancer - 2025-08-21

In a recent study, eighty-eight per cent of the respondents said they were in favour of body checking. Sixty-four per cent said they did not think there would be more injuries. Photo: Istock/vencavolrab In 2022, Sweden became the first country in the world to allow body checking in women's ice hockey. Major hockey nations are now following Lund University's research on the consequences of tougher

https://www.medicine.lu.se/article/swedish-female-ice-hockey-players-favour-body-checking - 2025-08-21